80 research outputs found

    Enacting the entrepreneurial self:Public-Private Innovation as an actualization of the neoliberal market dispositive

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    Drawing on Foucault’s writings on power, neoliberalism, and the dispositive, this article analyses the identity politics that is immanent in a new collaborative practice between the public and private sector called public-private innovation (PPI). We argue that PPI is an element in actualizing a neoliberal market dispositive through inclining subjects to work on themselves in order to actualize their entrepreneurial self, thereby disconnecting them from their public service identity. The construction of two narratives supports the constitution of the political space of PPI: the fiery soul narrative and the need narrative. An important part of this identity politics is the construction of the narrative of the individual entrepreneur. Rather than expressing new public governance in the public sector, PPI actualizes a dispositive that marketizes public services as part of a neoliberal agenda. The narrative of PPI distracts from the marketization of public sector and leaves no other space for public-sector employees than to constitute themselves within contradictory feelings of enthusiasm and anxiety, determination and self-blame, responsibility and inadequacy, and bustle and confusion

    Characteristics Associated with Serological Covid-19 Vaccine Response and Durability in an Older Population with Significant Comorbidity:The Danish Nationwide ENFORCE Study

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    OBJECTIVES: To identify individual characteristics associated with serological COVID-19 vaccine responsiveness and durability of vaccine-induced antibodies. METHODS: Adults without history of SARS-CoV-2 infection from the Danish population scheduled for SARS-CoV-2 vaccination were enrolled in this parallel group, phase IV study. SARS-CoV-2 Spike IgG and Spike-ACE2-receptor-blocking antibodies were measured at days 0, 21, 90 and 180. Vaccine responsiveness was categorized according to Spike IgG and Spike-ACE2-receptor-blocking levels at day 90 post-1(st) vaccination. Non-durable vaccine-response was defined as day 90 responders that no longer had significant responses by day 180. RESULTS: Of 6544 participants completing two vaccine doses (median age 64, interquartile range:54–75), 3654 (55.8%) received BTN162b2, 2472 (37.8%) mRNA-1273, and 418 (6.4%) ChAdOx1 followed by a mRNA vaccine. Levels of both types of antibodies increased from baseline to day 90 and then decreased to day 180. The decrease was more pronounced for levels of Spike-ACE2-receptor-blocking antibodies than for Spike IgG. Proportions with vaccine hypo-responsiveness and lack of durable response were 5.0% and 12.1% for Spike IgG; 12.7% and 39.6% for Spike-ACE2-receptor-blocking antibody levels, respectively. Male sex, vaccine type and number of co-morbidities were associated with all four outcomes. Additionally, age >=75y was associated with hypo-responsiveness for Spike-ACE2-receptor-blocking antibodies (adjusted odds-ratio:1.59, 95% confidence interval:1.25–2.01) but not for Spike IgG. CONCLUSIONS: Comorbidity, male sex and vaccine type were risk factors for hypo-responsiveness and non-durable response to COVID-19 vaccination. The functional activity of vaccine-induced antibodies declined with increasing age and had waned to pre-2(nd) vaccination levels for most individuals after 6 months
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